Module 1: Introduction and welcome: Dr Shubhi Kulshrestha from Medical Learning Hub welcomed the speaker and all the participants. She then introduced the speker Dr.(Prof.) Meenu Walia, Senior Director - Medical Oncology, Max Super Speciality, Noida. All the general instructions were explained and the first poll was raised.
Module 2: Diagnosis and management of Chronic myeloid leukemia with case presentation: Dr.(Prof.) Meenu Walia, Senior Director - Medical Oncology, Max Super Speciality, Noida shared her clinical experience in maintenance therapy for acute myeloid leukemia along with clinical case presentation. She covered following points in brief:
- A clinical case presentation of chronic myeloid leukemia
- A brief history of the Philadelphia chromosome.
- The survival rates of chronic myeloid leukemia patients with appropriate therapy
- The presentation of chronic myeloid leukemia patient when coming to the clinician and the recommended investigations
- The ideal investigations like bone marrow karyotyping, Fluorescence in situ Hybridization (FISH test) to confirm Philadelphia chromosome
- Evolution of diagnosis of chronic myeloid leukemia
- Importance of early diagnosis of chronic myeloid leukemia
- Treatment of chronic myeloid leukemia
- The steps to monitor therapeutic response for a clinician
- The brief explanation of hematologic, cytogenetic and molecular response in chronic myeloid leukemia
- Evolution of treatment in chronic myeloid leukemia management
- A clinical perspective of BCR-ABL reduction and its importance
- Different Molecular response and long term outcome in chronic myeloid leukemia
- Importance of achieving deep molecular response beyond MMR
- Current recommendations for molecular monitoring in chronic myeloid leukemia
- The aim of treatment of chronic myeloid leukemia in 2020 is changed from preventing progression to operational cure
- The brief explanation of survival rates from IRIS study design
- Predictors of prolong survival in chronic myeloid leukemia
- Disease progression with imatinib with intolerance and resistance response
- Updated ELN 2013 recommendations focus on molecular response as a first line therapy
- Milestone molecular responses - ELN recommends repeat testing before changing therapy
- Update on ELN 2020 recommendations
- A brief overview of NCCN guidelines version 2.2023 on Chronic Myeloid Leukemia
- A brief on ESMO 2017 guidelines in response to incorporation of MR4 as optimal response milestone
- Prognostic scoring systems for CP-CML
- Toxicity spectrum of TKIs in chronic myeloid leukemia
- Individualizing therapy in Chronic Myeloid Leukemia - TKIs for patients with specific history or comorbidities
- Pregnancy and TKIs
- The selection of therapy between 1st and 2nd generation TKIs at diagnosis
- Criteria and monitoring while discontinuing TKIs
Module 3: Q & A: Several questions were asked by the attendees which were answered by Dr. Meenu Walia after her presentation.
Module 4: Vote of thanks: Dr Shubhi delivered a vote of thanks with all the participants, speaker and sponsors for supporting in the event. Second poll was raised.
We wish you a great learning experience!
- Introduction & welcome note
- Speaker session:Diagnosis and management of Chronic myeloid leukemia (CML) with case presentation: Dr Meenu Walia, Senior Director - Medical Oncology, Max Super Speciality Hospital, Patparganj, Vaishali & Noida.
- Question & Answer
- Vote of thanks
