Module 1: Introduction and welcome: Dr Shubhi Kulshrestha from Medical Learning Hub welcomed speaker and all the participant. She then introduced Dr. Byreddy Poojitha, consultant, Hematology, Care Hospital, Hyderabad who was the speaker. Post that all the general instructions were explained and the first poll was raised.
Module 2: Maintenance therapy for acute myeloid leukemia (AML): Dr. Poojitha, Consultant Haematology at Care hospital, Hyderabad shared her clinical experience in maintenance therapy for acute myeloid leukemia along with clinical case presentation. She covered following points in brief:
- Introduction of AML and historic structure of AML therapies in adults.
- Maintenance therapy in treatment paradigm of the patients
- Requirements of chemo needed in one patient
- The concept of maintenance therapy and how to define a maintenance therapy in treatment
- The concept of maintenance therapy in AML.
- The characteristic of ideal maintenance agent
- Utilization of maintenance therapy when there is MRD negative state
- Evolution of maintenance therapy in AML
- Findings from clinical trials, chemotherapy based non-HSCT patients
- Immune adjuvants have been utilized in studying the role of maintenance therapy
- Role of checkpoint inhibitors
- Hypomethylating agents and its mechanism
- Role of Azacytidine in AML
- Few clinical trial studies on Azacytidine
- Explanation of Preemptive study
- Different example of combination therapies, targeted therapies, other FLT3 inhibitors, IDH inhibitors, IDH inhibitors POST HSCT, Hypomethylating agents and its clinical outcomes
- Boosting post transplant immune surveillance
- The different maintenance therapy approaches and their clinical utility based on MD Anderson experience
- Unmet needs in case of maintenance therapy
Module 3: Q & A: Several questions were asked by the attendees during the live session which were answered by Dr. Poojitha after her presentation.
Module 4: Vote of thanks: Dr Shubhi shared vote of thanks with all the participants. Second poll was raised.
We wish you a great learning experience!
Introduction & welcome note
Speaker 1: Maintenance therapy for acute myeloid leukemia: Dr Poojitha Reddy
Speaker 2: Case presentation
Question & Answer
Vote of thanks
